An integrated approach is recommended in bullous pemphigoid
نویسندگان
چکیده
Commentary on ‘Coexistence of bullous pemphigoid with neuropsychiatric comorbidities is associated anti-BP230 seropositivity’ by Ständer et al. Through this research, Sonja Stander and collaborators found a way to detect the link between (BP) comorbidities1 like Alzheimer disease (AD), Parkinson (PD) other neurological diseases (ND) in such patients. A blood test can seropositivity, emerged as an independent predictor comorbidity BP. What does that mean for clinical dermatologist? The dermatologist receiving new patient BP should look at seropositivity any cognitive impairment (CI) together mental health disorders. There are easy tools diagnose CI rapidly Mini-Mental State Examination (MMSE) Montreal Cognitive Assessment (MonCA). If positively detected, it important know prognosis worse risk relapse much higher. Those patients be referred neurologists further assessments treatment. Remarkably, study2 38 patients, was up 28% MMSE 89% MoCA scale tends have higher sensitivity diagnosis mild (MCI). This screening supported study fact markedly high ratio who were screened positive after being excluded from existing ND, verified neurocognitive dysfunctions. Patients early detection even dementia been reported more effectively treated thus could improve their quality life.3 We not forget take pressure because values lead strokes vascular which also trigger factor However, some adverse reactions psychopharmacology drugs affect skin. Drugs particularly elevated included periciazine, melperone, haloperidol, biperiden risperidone. Moreover, psychiatric side effects oral corticosteroids frequently prescribed extended include mood disorders, anxiety, panic delirium, agitation, insomnia or suicidal behaviour.4 has systemic therapies. putative antibiotics, beta-blockers, non-steroidal anti-inflammatory (NSAIDs), diuretics and, recently, anti-tumour necrosis (TNF) used treatment malignancies.5 mind too. It seems significant develop PD during follow-up.6 confused extrapyramidal antipsychotics. Here collaboration psychiatrists essential. Finally, nationwide retrospective Finnish population,7 several correlations strongest developing multiple sclerosis (MS). Amongst diseases, corresponding schizophrenia personality pruritus precede blistering skin months, disturb sleeping, strongly affecting individual’s cognition well. research help those before diagnosing them sine materia anxious In conclusion, all these data inviting into account follow-up professionals specialists. None declare. None.
منابع مشابه
Bullous pemphigoid
Disease summary: Bullous Pemphigoid is an acquired, chronic, blistering autoimmune subepidermal bullous disease in which autoantibodies are directed against component of basement membrane zone of the skin [1]. It is characterized by formation of cutaneous bullae on the skin and mucous membrane. The pathogenesis involves migration of inflammatory cells into subepithilial tissues due to activatio...
متن کاملBullous pemphigoid.
B ullous pemphigoid is an autoimmune disease, which means that the cells in the body that normally fight infection attack the body instead. The body’s immune system is confused and makes an antibody (type of protein used to fight infection) that targets a part of the skin that normally holds it together. The attack on the skin causes blisters (firm, fluid-filled bubbles on the skin) to form. Th...
متن کاملA new approach on bullous pemphigoid therapy.
Bullous pemphigoid (BP) is the most common subepidermal autoimmune blistering skin disease seen in the elderly. The prognosis of BP is poor, since the 1-year mortality rate has been reported to range from 25% to 40% in recent studies [1]. Corticosteroids have been so far the mainstay of therapy [2]. Antibiotics and immunosuppressants, such as cyclophosphamide and azathioprine, have also been us...
متن کاملLocalized genital bullous pemphigoid; A case report
Bullous pemphigoid (BP) is an autoimmune bullous disorder with urticarial pruritic papules and plaques and tense bullae in flexural surfaces of body. The localized form of the disease is a rare variant which can be triggered by different stimuli. Hereunder, we report a patient with the local type involving genitalia without any triggering factors.
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ژورنال
عنوان ژورنال: Journal of The European Academy of Dermatology and Venereology
سال: 2021
ISSN: ['1468-3083', '0926-9959']
DOI: https://doi.org/10.1111/jdv.17600